Rabies

Updated: Apr 2, 2020


DISCLAIMER:

Rabies is a very serious virus that is deadly to companion animals and people. This article is for educational purposes only. We advocate for informed consent and the right to make the best decision for your companions without fear, persecution, being threatened or coerced into vaccinating. We advocate for the concept of vaccination philosophies but currently do not agree with how they are made, the ingredients in them or how they are administered. Read and vaccinate at your own risk.

Vaccinating is hot a topic among many pet owners especially those that either have experienced a reaction in the past including death or those that prefer a more natural life style for their companions. This article is a summary exploration of all things rabies. HISTORY: The rabies virus’ family name Rhabdovirus originates (1) from Sanskrit. It comes from the word “rabhas” which means “to do violence”. (2)


Rabies isn’t anything new. Cuneiform tablets dating back all the way to 4000 years ago speak of this dangerous virus (3, 4). Throughout many periods of history punishment was severe for allowing a dog with rabies to spread the disease to humans via a bite.

From 2008 to 2017 23 people contracted rabies in the United States, but 11 of those were traced back to bats. In addition, eight were contracted outside the US and none were domestic companion dogs or cats (5). PREVELANCE

Domestic dogs make up 1% of REPORTED rabid animals (6,7) however, there are no averages for the spread of rabies via companion animal bites in the US because it is so rare. Most occur in third world countries and most studies don’t distinguish between stray and domestic pet dogs, however with most bites occurring in third world countries most ARE stray dogs. Does rabies exist in the United States? Originally mass vaccination was common in the 1940’s in a time when human rabies was extremely prevalent. The result of this dedicated period of time inoculating has created an environment where rabies has virtually been eradicated in the companion animal population including the CDC stating its eradication in 2007 of canine rabies (8, 9, 10).

What about cats? While we have looked everywhere including scientific databases and government websites we have really only found statistics and information on rabies in canines and wild animals. No cat-to-cat rabies transmission has been recorded, and no feline strain of rabies virus is known (11).

In 2018 6.2% reported cases were in cats.


In 2017 21,187 cats were tested for rabies. Of those tested cats 276 or 3.1% tested positive (6). While this was a 7.4% increase from the previous year the 1.3% (276 cats) of the cats submitted for rabies were rabid, no reports were made that they bite humans and there was no distinguishing between pet and stray cats. Furthermore according to The Humane Society there are 94.2 million PET cats (13).Taking this number into account that would mean 0.00000292993% of the total pet cat population had rabies. There are 30-40 million cats estimated to be stray, abandoned and feral cats (13). If we apply these 276 cats to solely this population of cats 0.0000092%-0.0000069% were rabid. Combine the pet and stray population we have about 124.2-134.2 million cats giving us 0.00000222222%-0.00000205663% rabid cats. Rabies in cats is extremely rare. According to the CDC, domestic animals, including pets, accounted for only 7.6% of reported rabies cases in the U.S. in 2015, the last year for which statistics were available. There has not been a single confirmed case of cat-to-human rabies in the U.S. in the past 40 years. In fact, only two human rabies cases have been attributed to cats since 1960.

Small animals that cats often hunt like squirrels, chipmunks, and mice almost never contract rabies. (14). Primarily wild animals are the ultimate concern. (15, 16, 17)

In 2017 1,433 (32.2%) bats, 1,275 (28.6%) raccoons, 939 (21.1%) skunks, 314 (7.0%) foxes, 276 (6.2%) cats, 62 (1.4%) dogs, and 36 (0.8%) cattle make up the reported and tested animals with rabies (6).

According to the CDC’s website human rabies is quite rare with only about 1-3 cases a year and 23 cases occurring between 2008-2017. Eight of those were acquired outside the united states. This means that 1-2 in 324,000,000 chances of death in humans. Keep in mind most of these statistics aren’t referring to rabies bites from DOMESTIC cats and dogs IN the United States. Most are wild or stray animals majorly in third world countries.

In 2010, there were 6,154 cases of rabies in animals, and 2 human cases were reported in the US and Puerto Rico (one rabid dog [bitten in another country], one bat and one mongoose [in Puerto Rico]. None sought medical help immediately after the incident and failed to see a doctor even a week later.

While wildlife has accounted for 90% of rabies cases in the US, of the animal cases reported, only 5% were feline (5) The biggest concern for rabies occurs primarily in third world and less developed countries. In India and Africa (18), the death toll is still numbered at around 60,000 human deaths each year (19, 20). Most of these are young children(21). Africa and Asia are primarily a big problem because there are no laws or regulations for rabies nor is there control of stray animals like dogs (22).

The World Health Organization and U.S. Centers for Disease Control refer to this as neglected tropical disease (23). There are known ways to control rabies via knowledge treating bites, reporting and tracking as seen in first world countries, but this is a serious problem in third world countries (24, 25).

Fear not efforts are being made. The Caribbean and Latin America is a great example. They are helping to reduce the prevalence by vaccinating, surveillance and education in addition to proper pre and post prophylaxis of rabies. In fact, many Latin American countries are now human rabies free. Other areas that are still affected are seeing drastic drops in numbers. In 2010 canine rabies went from 25,000 cases in 1980 to only 300 and the incidence of dog to human cases went from 300 to 10 in the same time span (26).

Please note THIS IS THIRD WORLD COUNTRIES NOT FIRST WORLD. Third world countries and vaccine protocols are one story, countries like the USA is another (6, 27, 29).

HOW

Rabies is fairly easy to spread. According to the Global Alliance for Rabies Control “Blood, feces, and urine cannot transmit the virus. Most infections will occur directly by animal bites”. It is passed via the saliva and is very serious because the disease infiltrates the nervous system (22).

Georg Gottfried Zinke a German researcher was able in 1804 to spread the disease to animal tissues just with rabid saliva without a single bite being involved. Again, this was repeated with a human victim (30, 31).

Another experiment took tissue from a rabid cat and put it in contact with the wound of a dog resulting in the dog becoming rabid.

Once in the nerves it finds its way to the brain. Often this is fairly quick, but it could take weeks or months (32). depending on how close the bite was to the head (33). After the virus has spread to the current victim’s brain it’s time to find another host. The virus moves back down to the salivary glands producing an abundance of saliva to pass the disease onto another victim. This is why many rabid animals’ foam at the mouth (22, 34, 35)

Not any old animal carries rabies, it is primarily spread by carnivores (36).

While cows, sheep and horses can get rabies, it’s pretty much a dead end for rabies as it doesn’t spread from sheep to sheep for example and thus dies. In America the most common carriers of rabies often include skunk, raccoon, bats, coyotes and fox.

raccoons (28.6% [1,275]), skunks (21.1% [939]), and foxes (7.0% [314]).


“Figure 1— Distribution of major RVVs among mesocarnivores in the United States and Puerto Rico. Black diagonal lines represent distribution of fox RVVs (Arizona gray fox and Texas gray fox RVVs). Solid borders represent RVV distributions from 2013 through 2017; dashed borders represent the previous 5-year distributions from 2012 through 2016” (6).


WHAT DOES A RABID ANIMAL LOOK LIKE? Most people may not have personally seen what a rabid animal is like, but we’ve all heard of what they look like. Many of these critters are out during the day, being nocturnal this is abnormal behavior. Many are “friendly” and while normally scared of humans, will come right up to you. They will be walking like a drunk person, awkwardly moving and swaying. Finally, they will attack often in the foam of a foamy bite.

SYMPTOMS

There are wide range of symptoms found in the rabid. These can include: Behavior changes Deviation from pack behavior (free roaming) Anorexia Paranoia Irritability Abnormally hyper excitability Ataxia Changes in temperament Making strange noises Paralysis (typically what kills the victim) Eating things they shouldn’t primarily undigestible items Restlessness Rage/Fury Fear of water (due to paralysis intense spasms can occur) (11, 37, 38, 39)

TREATMENT

Post-exposure prophylaxis was developed quite a long time ago. It all started with a 9-year-old boy who suffered 14 bites across his hand and legs in 1885 from a dog who was quickly shot by the police. Louis Pasteur, a well-known French scientist, injected the boy 13 times over 10 days with an inoculation made from a rabbit infected with rabies. As the days went by the strength of the injections increased. With the last inoculation being made from a rabbit that had died within just 7 days of being injected with rabid substances from another rabbit infected by the disease. The theory was the virus was less potent as rabbit after rabbit was injected with the prior rabid rabbit making the exposure less deadly to the human victim. This is known as serial passage. As it’s passed from species to species the virus is less used to that particular animal reducing virulence and thus less dangerous to people. It however is strong enough to develop immunity to the virus you find in nature.


The boy ended up surviving making this method the start of Post-exposure prophylaxis procedures and identifying a very unique time frame for the treatment of the virus (40, 41).

Post Exposure Prophylaxis is essentially 100% effective in preventing rabies from fully developing in humans. The few that it didn’t work on suffered deadly allergic reactions and thus could not be cured (42, 43).

Ultimately wound care is one of the best things one can immediately do for a rabies bite. It may seem silly but thoroughly washing the wound is paramount. This obviously is essential when educating citizens of third world countries when it comes to rabies. (42, 44, 45, 46, 47)

WHAT HAPPENS IF I OR MY COMPANION ARE BIT OR SUSPECTED OF RABIES?

Because Rabies is a serious issue if confronted with it, calling your local health department is the responsible thing to do.

If your companion is suspected of rabies or being bitten by a rabid animal, they will be required to be quarantined for 10 days (48, 49). Should symptoms such as erratic behavior or paralysis occur the animal will be put to sleep and the brain will be examined to determine if the animal was rabid (50, 51, 52).

If a human is bitten post-exposure prophylaxis is administered in the form of several antibody doses to avoid the spread of rabies to humans (53).

Now are you liable if your companion bites someone and they are NOT up to date on their rabies vaccine? In short yes you are liable purely because your animal caused harm to someone/something else. It would also be hard to believe that you are less liable if your cat IS up to date on their rabies vaccine. Why? Because regardless someone may need medical care for their injuries. Are you liable if they are not current? Technically yes but only if someone asks or is walking around town requiring to see vaccine records. How practical is that? Not very as you would already be surveyed. Should you be approached really the worst-case scenario is your companion will be quarantined for 10 days and observed to see if they have rabies.

RABIES AND THE LAW

Ok so you are fine not vaccinating anything that isn’t “legally” required but what about the big R, the Rabies Vaccine?

Unfortunately, even if some states are now providing medical exemptions and some countries are not requiring vaccination, individual cities and counties create their own rules when it comes to vaccination which include requiring yearly vaccines. (54)

Rabies laws vary from state to state because each state’s Department of Health makes these laws. This is a human government body, not animal (55, 56). While potentially, judicially sound, ironically these laws have no backing in immunology or science.

VACCINES AND IMMUNOLOGY Immunologists study the immune system; they have identified what is called duration of immunity (DOI) and that this duration is long for virus-based vaccines (57, 58, 59, 60).

They also have identified that vaccinating more does not equate to more protection and a new immune response being elicited. Why listen to immunologists over a veterinarian specifically? Because immunologists aren’t selling vaccines, they are providing information about the immune system and how it operates. Veterinarians are great for many things but if they aren’t looking for or acknowledge the problems vaccines cause and money is a driving force for this blindness than that’s a concern and conflict of interest. It has been a well-known fact that annual vaccination is no longer recommended, yet 60% of veterinarians are still recommending it (61, 62)

Vaccinations make up 50%-70% of sales at veterinary clinics (63). Most vaccines generally cost about $0.60-$0.90 to make however veterinary clinics charge about $15-$30 per vaccine. (63, 64, 65, 66, 67). Lower the frequency of vaccinations, lower your profit.

Unbeknownst to many the American Association of Feline Practitioners (AAFP) released an official statement in 2000. This statement advised against annual vaccination. This was based on a study performed by Cornell University in which after vaccination, 7 years later immunity still existed (68).

ANNUAL VACCINATION Technically there is no difference in the “immunity” 1 year and 3-year rabies vaccines provide. The labels simply represent the time span animals were studied but the same vaccine was evaluated (69, 70, 71).


So far other challenges have been suggested implying immunity for 7 or more years. A fund entitled The Rabies Challenge Fund are the top researchers in determining the duration of immunity vaccines provide and having legislation comply with this science. They are currently in their fourth year of determining duration of immunity 7 years after inoculation (72). “The following was printed in a well-respected, peer-reviewed textbook that is updated every four years). The authors include veterinary immunologists Ronald Schultz (University of Wisconsin) and Tom Phillips (Scrips Research Institute).

They are addressing vaccination efficacy directly in this excerpt:

A practice that was started many years ago and that lacks scientific validity or verification is annual revaccination. Almost without exception there is no immunologic requirement for annual revaccination. Immunity to viruses persists for years or for the life of the animal…… Furthermore, revaccination with most viral vaccines fails to stimulate an anamnestic (secondary) response…. The practice of annual vaccination in our opinion should be considered of questionable efficacy…” (73)

FEAR

Fear is a big influencer when it comes to government and professional education as well in making decisions. Statements like “you’re going to kill your pet” “you are going to kill other people’s pets” “did you hear about Susie’s cat….?”or “that’s illegal” are meant to scare you into making a decision without informed consent or true education on both sides of the topic (74, 75, 76, 77, 78).

PROBLEMS WITH THE RABIES VACCINE

The rabies vaccine contains the killed rabies virus therefore the virus does not replicate in your cat like a modified live vaccine does (79, 80).

Killed vaccines are vaccines that have the main pathogen inactivated by heating or chemical application. While considered “safer” than modified live vaccines (81), they require larger amounts of the pathogen, administration of multiple doses and require adjuvants to activate an immune response which is often weaker and shorter in duration (82, 83).

However, on the other hand modified live vaccinations contain viruses that are still active more closely resembling the real pathogen that would be encountered in nature. While they produce stronger and longer immune responses, they are less safe resulting in shedding, immunosuppression and even cause vaccine induced disease (81, 84, 85, 85, 87). WHAT ARE THE SIGNS OF A RABIES VACCINE REACTION? Above we presented the symptoms of the rabies virus in a rabies victim. When we start hearing of complaints after a rabies vaccine, we see many similar problems we see in rabies victims some we may not think were even related:

  • Does your companion eat things they shouldn’t be? (feces, stones, wood etc.)

  • Is there a fear of water (biting water from the sink, agitation around water sources, etc.)

  • Fear of storms especially lightening

  • Aggressive and ready to fight or bite

  • Fear of strangers

  • Paralysis

  • Erratic breathing or reverse sneezing

  • Destroying toys, blankets and bedding

  • Seizures, incoordination, tics

  • Restlessness or desire to roam aimlessly

  • Erratic behavior when confined

  • Self harm like excessive scratching and biting

  • No interest in food

  • Diluted pupils

  • Inflammation of the heart, abnormal heart function, heart failure etc.

  • Dry eyes

  • Change in muscle movement

(88)

Will Falconer, a fore leader on natural rearing and vaccine practices has documented the following in response to damage caused by the rabies vaccine:

  • Immune mediated hemolytic anemia (50% fatality rate)

  • Epilepsy

  • Cancer at the injection site (used to be called "Vaccine-associated sarcoma")

  • Tumors elsewhere, or benign tumors changing to malignant ones

  • Laryngeal paralysis that often progresses to rear end paralysis

  • Degenerative myelitis

  • Chronic inflammatory bowel disease

  • Chronic allergic skin (and/or ear) disease

  • Hyperactivity

  • Hypersexuality

  • Hypersensitivity

  • Aggression, suspicion, fearfulness

Reactions don’t always happen immediately; they can happen later down the road. Why is this a) think on a human scale (which can be applied to animals) you eat McDonald’s for years. You don’t have a heart attack the first time you eat there (although that’s not out of the question) you have it down the road (90, 91) b) vaccines contain so many factors that stress our bodies down to the epigenetic level. It turns on and off genes (92, 93, 94, 95, 96, 97) and c) you have to be open to making the connection. Most owners don’t take notes they only have general ideas of when events and situations happen failing often to make correlations.

RABIES VACCINE AND OTHER DISEASE CORRELATIONS Since the early 90’s it has been well know that vaccines are correlated with malignant tumors in cats (98,99).


This is often why rabies vaccines are administered in a leg or the tail (100, 101, 102).

You can “easily” amputate this part without killing the animal. Without these areas being the location for injection, even surgery doesn’t prevail (103, 104).

Many feline vaccines including the rabies vaccine are grown on feline kidney cell lines. When harvesting the virus kidney proteins also become incorporated into the vaccine. So, when a cat is vaccinated with the rabies vaccine not only is the body producing an “immune response” to rabies it also creates antibodies to feline kidney cells (105, 106, 107, 108, 109). Thus, the rabies vaccine has been correlated to high prevalence of kidney failure in cats. Essentially the body is attacking itself and its own immune system.

CAN’T YOU JUST DETOX?